Full name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: 14-3-3GAMMA; DEE56; EIEE56; PPP1R170

Summary: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

Expression: Broad expression in brain (RPKM 260.6), fat (RPKM 131.1) and 22 other tissues

Gene size: 32193bp

Exon count: 2