Full name: exportin 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CRM-1; CRM1; emb; exp1

Summary: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]

Expression: Ubiquitous expression in testis (RPKM 38.6), lymph node (RPKM 33.8) and 25 other tissues

Gene size: 60764bp

Exon count: 31