Wdr35 WD repeat domain 35 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 74682)
Source: NCBI Gene (ID 74682)
Symbol: Wdr35
Full name: WD repeat domain 35
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 4930459M12Rik; 4931430C06; mKIAA1336
Summary: Involved in cilium assembly. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in axoneme; centrosome; and ciliary basal body. Part of intraciliary transport particle A. Is expressed in several structures, including choroid plexus; limb mesenchyme; lobar bronchus epithelium; metanephros; and sensory organ. Used to study short-rib thoracic dysplasia 7 with or without polydactyly. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome; cranioectodermal dysplasia 2; and short-rib thoracic dysplasia 7 with or without polydactyly. Orthologous to human WDR35 (WD repeat domain 35). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in testis adult (RPKM 14.6), CNS E18 (RPKM 6.0) and 15 other tissues
Orthologs: human
Gene size: 54952bp
Exon count: 28