WIPF1 WAS/WASL interacting protein family member 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 7456)
Symbol: WIPF1
Full name: WAS/WASL interacting protein family member 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: PRPL-2; WAS2; WASPIP; WIP
Summary: This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Expression: Broad expression in lymph node (RPKM 61.9), appendix (RPKM 50.1) and 23 other tissues
Orthologs: mouse
Gene size: 123340bp
Exon count: 18