Full name: GLE1 RNA export mediator (yeast)

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 4933405K21Rik; Gle1l

Summary: Predicted to enable several functions, including identical protein binding activity; inositol hexakisphosphate binding activity; and translation initiation factor binding activity. Predicted to be involved in mRNA export from nucleus; regulation of translational initiation; and regulation of translational termination. Predicted to act upstream of or within mRNA transport and protein transport. Predicted to be located in cytosol; microtubule organizing center; and nucleus. Predicted to be part of nuclear pore cytoplasmic filaments. Predicted to be active in cytoplasm. Is expressed in brain; cerebral cortex; and hippocampus. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 1. Orthologous to human GLE1 (GLE1 RNA export mediator). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in cerebellum adult (RPKM 15.0), CNS E18 (RPKM 14.4) and 28 other tissues

Gene size: 24024bp

Exon count: 16