Full name: sperm antigen with calponin homology and coiled-coil domains 1-like

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 4930470P14Rik; 4932439K10Rik; 9530057A13Rik; Cytsa; mKIAA0376

Summary: Enables beta-catenin binding activity. Acts upstream of or within several processes, including anterior neural tube closure; negative regulation of protein depolymerization; and positive regulation of protein kinase B signaling. Located in cell-cell junction; cytoplasm; and cytoskeleton. Part of filamentous actin. Is expressed in 1st branchial arch maxillary component; branchial arch; eye; fronto-nasal process; and limb. Human ortholog(s) of this gene implicated in Opitz GBBB syndrome type II and oblique facial clefting 1. Orthologous to human SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in lung adult (RPKM 17.1), large intestine adult (RPKM 10.0) and 28 other tissues

Gene size: 100363bp

Exon count: 20