Sgip1 SH3-domain GRB2-like (endophilin) interacting protein 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 73094)
Source: NCBI Gene (ID 73094)
Symbol: Sgip1
Full name: SH3-domain GRB2-like (endophilin) interacting protein 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 3110007P09Rik; SGIP1alpha; gag
Summary: Enables microtubule binding activity and phospholipid binding activity. Acts upstream of or within plasma membrane tubulation and positive regulation of receptor-mediated endocytosis. Located in clathrin-coated vesicle and plasma membrane. Part of AP-2 adaptor complex. Is expressed in central nervous system; metanephros; small intestine; and testis. Orthologous to human SGIP1 (SH3GL interacting endocytic adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in frontal lobe adult (RPKM 10.0), cortex adult (RPKM 5.5) and 7 other tissues
Orthologs: human
Gene size: 218273bp
Exon count: 29