Full name: U2 small nuclear RNA auxiliary factor 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: FP793; RN; RNU2AF1; U2AF35; U2AFBP

Summary: This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in bone marrow (RPKM 35.4), colon (RPKM 24.4) and 25 other tissues

Gene size: 14623bp

Exon count: 11