Aplf aprataxin and PNKP like factor [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 72103)
Source: NCBI Gene (ID 72103)
Symbol: Aplf
Full name: aprataxin and PNKP like factor
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 2010301N04Rik
Summary: Predicted to enable DNA-(apurinic or apyrimidinic site) endonuclease activity; nuclease activity; and nucleotide binding activity. Acts upstream of or within double-strand break repair and regulation of isotype switching. Predicted to be located in nucleoplasm. Predicted to be active in nucleus and site of double-strand break. Orthologous to human APLF (aprataxin and PNKP like factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in liver E14 (RPKM 3.4), liver E14.5 (RPKM 3.0) and 28 other tissues
Orthologs: human
Gene size: 43838bp
Exon count: 11