TRIO trio Rho guanine nucleotide exchange factor [ Homo sapiens (human) ] - Gene - Data resources

7204

TRIO trio Rho guanine nucleotide exchange factor [ Homo sapiens (human) ]
Source: NCBI Gene (ID 7204)

Symbol: TRIO

Full name: trio Rho guanine nucleotide exchange factor

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ARHGEF23; MEBAS; MRD44; MRD63; tgat

Summary: This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Expression: Ubiquitous expression in brain (RPKM 8.0), spleen (RPKM 6.0) and 25 other tissues

Orthologs: mouse

Gene size: 366863bp

Exon count: 61