Full name: chaperonin containing TCP1 subunit 3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CCT-gamma; CCTG; PIG48; TCP-1-gamma; TRIC5

Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010]

Expression: Ubiquitous expression in testis (RPKM 72.7), adrenal (RPKM 56.4) and 25 other tissues

Gene size: 29325bp

Exon count: 16