Full name: canopy FGF signaling regulator 3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: 1600025D17Rik; 2410050O22Rik; CAG4A; ERDA5; PRAT4A; Tnrc5

Summary: This gene encodes a member of the canopy family of proteins. The encoded protein may play a role in the maturation of toll-like receptors. Homozygous knockout mice for this gene show reduced cell surface expression of toll-like receptors and an impaired immune response including reduced production of cytokines in a mouse model of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Expression: Ubiquitous expression in spleen adult (RPKM 22.5), adrenal adult (RPKM 22.5) and 28 other tissues

Gene size: 17003bp

Exon count: 7