TNS1 tensin 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 7145)
Source: NCBI Gene (ID 7145)
Symbol: TNS1
Full name: tensin 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: MST091; MST122; MST127; MSTP091; MSTP122; MSTP127; MXRA6; PPP1R155; TNS
Summary: The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Expression: Broad expression in fat (RPKM 95.5), lung (RPKM 38.8) and 21 other tissues
Orthologs: mouse
Gene size: 234192bp
Exon count: 48