Full name: complement C1q B chain

Gene type: protein coding

RefSeq status: REVIEWED

Summary: This gene encodes the B-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. [provided by RefSeq, Dec 2016]

Expression: Broad expression in spleen (RPKM 482.2), lymph node (RPKM 181.6) and 15 other tissues

Gene size: 8402bp

Exon count: 4