Dlg5 discs large MAGUK scaffold protein 5 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 71228)
Symbol: Dlg5
Full name: discs large MAGUK scaffold protein 5
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 4933429D20Rik; mKIAA0583
Summary: Predicted to enable beta-catenin binding activity and cytoskeletal protein binding activity. Involved in positive regulation of dendritic spine development; positive regulation of synapse assembly; and regulation of signal transduction. Acts upstream of or within several processes, including animal organ development; apical protein localization; and protein localization to adherens junction. Located in adherens junction; ciliary basal body; and postsynaptic density. Is expressed in several structures, including alimentary system; hemolymphoid system gland; lung; nervous system; and reproductive system. Orthologous to human DLG5 (discs large MAGUK scaffold protein 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in limb E14.5 (RPKM 14.4), genital fat pad adult (RPKM 13.1) and 24 other tissues
Orthologs: human
Gene size: 111968bp
Exon count: 34