Spag9 sperm associated antigen 9 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 70834)
Source: NCBI Gene (ID 70834)
Symbol: Spag9
Full name: sperm associated antigen 9
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 3110018C07Rik; 4733401I23Rik; 4831406C20Rik; JIP-4; JLP; JSAP2; JSAP2a; Jip4; Mapk8ip4; syd1
Summary: Enables several functions, including MAP-kinase scaffold activity; kinesin binding activity; and protein kinase binding activity. Acts upstream of or within several processes, including JNK cascade; positive regulation of MAPK cascade; and positive regulation of neuron differentiation. Located in perinuclear region of cytoplasm. Is expressed in central nervous system; dorsal root ganglion; retina; and trigeminal nerve. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and liver cirrhosis. Orthologous to human SPAG9 (sperm associated antigen 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E18 (RPKM 26.0), cerebellum adult (RPKM 26.0) and 26 other tissues
Orthologs: human
Gene size: 130126bp
Exon count: 35