Full name: transforming growth factor alpha

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: TFGA

Summary: This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Expression: Broad expression in esophagus (RPKM 11.6), gall bladder (RPKM 8.1) and 17 other tissues

Gene size: 106543bp

Exon count: 7