Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 70008)
Source: NCBI Gene (ID 70008)
Symbol: Ace2
Full name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 2010305L05Rik
Summary: Predicted to enable identical protein binding activity; peptidase activity; and virus receptor activity. Involved in positive regulation of cardiac muscle contraction and tryptophan transport. Located in brush border membrane and cytoplasm. Is expressed in several structures, including brain; cardiovascular system; extraembryonic component; genitourinary system; and respiratory system. Used to study COVID-19 and congestive heart failure. Human ortholog(s) of this gene implicated in several diseases, including avian influenza; cerebral malaria; hypertension (multiple); respiratory syncytial virus infectious disease; and severe acute respiratory syndrome. Orthologous to human ACE2 (angiotensin converting enzyme 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in large intestine adult (RPKM 49.9), small intestine adult (RPKM 19.5) and 3 other tissues
Orthologs: human
Gene size: 49077bp
Exon count: 19