TCF7L2 transcription factor 7 like 2 [ Homo sapiens (human) ] - Gene - Data resources

6934

TCF7L2 transcription factor 7 like 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 6934)

Symbol: TCF7L2

Full name: transcription factor 7 like 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: TCF-4; TCF4

Summary: This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]

Expression: Ubiquitous expression in fat (RPKM 12.8), colon (RPKM 11.3) and 25 other tissues

Orthologs: mouse

Gene size: 217432bp

Exon count: 20