Kmt2e lysine (K)-specific methyltransferase 2E [ Mus musculus (house mouse) ] - Gene - Data resources

69188

Kmt2e lysine (K)-specific methyltransferase 2E [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 69188)

Symbol: Kmt2e

Full name: lysine (K)-specific methyltransferase 2E

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1810033J14Rik; 9530077A04Rik; D230038D11Rik; Mll5; NKp44L

Summary: Predicted to enable enzyme binding activity and methylated histone binding activity. Involved in several processes, including DNA methylation; erythrocyte differentiation; and neutrophil activation. Predicted to be located in nuclear body and transcriptionally active chromatin. Predicted to be part of protein-containing complex. Is expressed in several structures, including alimentary system; eye; heart; metanephros; and nervous system. Human ortholog(s) of this gene implicated in autistic disorder and cervical cancer. Orthologous to human KMT2E (lysine methyltransferase 2E (inactive)). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E14 (RPKM 16.9), whole brain E14.5 (RPKM 16.4) and 28 other tissues

Orthologs: human

Gene size: 71200bp

Exon count: 28