Full name: peptidylprolyl isomerase (cyclophilin)-like 1

Gene type: protein coding

RefSeq status: PROVISIONAL

Also known as: 1110060O10Rik; Cypl1

Summary: Predicted to enable cyclosporin A binding activity; disordered domain specific binding activity; and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in mRNA splicing, via spliceosome and protein peptidyl-prolyl isomerization. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be part of U2-type catalytic step 2 spliceosome. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human PPIL1 (peptidylprolyl isomerase like 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in liver E14.5 (RPKM 35.3), CNS E11.5 (RPKM 34.7) and 28 other tissues

Gene size: 13137bp

Exon count: 4