Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 68652)
Source: NCBI Gene (ID 68652)
Symbol: Tab2
Full name: TGF-beta activated kinase 1/MAP3K7 binding protein 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 1110030N06Rik; A530078N03Rik; Map3k7ip2; mKIAA0733
Summary: Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and zinc ion binding activity. Predicted to be involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of protein kinase activity; and response to lipopolysaccharide. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human TAB2 (TGF-beta activated kinase 1 (MAP3K7) binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in limb E14.5 (RPKM 18.4), CNS E11.5 (RPKM 13.0) and 28 other tissues
Orthologs: human
Gene size: 50628bp
Exon count: 11