Ints1 integrator complex subunit 1 [ Mus musculus (house mouse) ] - Gene - Data resources

68510

Ints1 integrator complex subunit 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 68510)

Symbol: Ints1

Full name: integrator complex subunit 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1110015K06Rik

Summary: Acts upstream of or within U2 snRNA 3'-end processing; inner cell mass cell proliferation; and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process. Located in nucleus. Is expressed in early conceptus. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies. Orthologous to human INTS1 (integrator complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in thymus adult (RPKM 35.7), adrenal adult (RPKM 20.2) and 28 other tissues

Orthologs: human

Gene size: 24419bp

Exon count: 47