Pdhb pyruvate dehydrogenase (lipoamide) beta [ Mus musculus (house mouse) ] - Gene - Data resources

68263

Pdhb pyruvate dehydrogenase (lipoamide) beta [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 68263)

Symbol: Pdhb

Full name: pyruvate dehydrogenase (lipoamide) beta

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2610103L06Rik

Summary: Predicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to contribute to pyruvate dehydrogenase (NAD+) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Predicted to act upstream of or within mitochondrial acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; heart; integumental system; and nervous system. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human PDHB (pyruvate dehydrogenase E1 subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in heart adult (RPKM 138.5), placenta adult (RPKM 75.5) and 25 other tissues

Orthologs: human

Gene size: 7313bp

Exon count: 11