Spire1 spire type actin nucleation factor 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 68166)
Source: NCBI Gene (ID 68166)
Symbol: Spire1
Full name: spire type actin nucleation factor 1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 6030430B19Rik; Spir-1
Summary: Predicted to enable actin binding activity. Involved in several processes, including cytoskeleton organization; cytoskeleton-dependent cytokinesis; and positive regulation of mitochondrial fission. Acts upstream of or within Golgi vesicle transport; behavioral fear response; and dendritic spine development. Located in Golgi apparatus; cell cortex; and cytoplasmic vesicle membrane. Is integral component of mitochondrial outer membrane. Colocalizes with cleavage furrow. Is expressed in central nervous system; dorsal root ganglion; genitourinary system; liver; and spleen. Orthologous to human SPIRE1 (spire type actin nucleation factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in cerebellum adult (RPKM 16.5), frontal lobe adult (RPKM 16.3) and 22 other tissues
Orthologs: human
Gene size: 124602bp
Exon count: 20