STK11 serine/threonine kinase 11 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 6794)
Source: NCBI Gene (ID 6794)
Symbol: STK11
Full name: serine/threonine kinase 11
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: LKB1; PJS; hLKB1
Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers. [provided by RefSeq, May 2022]
Expression: Broad expression in testis (RPKM 28.3), spleen (RPKM 10.4) and 25 other tissues
Orthologs: mouse
Gene size: 22654bp
Exon count: 10