Mcm8 minichromosome maintenance 8 homologous recombination repair factor [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 66634)
Source: NCBI Gene (ID 66634)
Symbol: Mcm8
Full name: minichromosome maintenance 8 homologous recombination repair factor
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 5730432L01Rik
Summary: Predicted to enable several functions, including chromatin binding activity; mismatch repair complex binding activity; and single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Involved in double-strand break repair via homologous recombination; female gamete generation; and male gamete generation. Part of MCM8-MCM9 complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and vibrissa. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 10. Orthologous to human MCM8 (minichromosome maintenance 8 homologous recombination repair factor). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E11.5 (RPKM 5.2), liver E14 (RPKM 3.0) and 23 other tissues
Orthologs: human
Gene size: 28057bp
Exon count: 19