Iscu iron-sulfur cluster assembly enzyme [ Mus musculus (house mouse) ] - Gene - Data resources

66383

Iscu iron-sulfur cluster assembly enzyme [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 66383)

Symbol: Iscu

Full name: iron-sulfur cluster assembly enzyme

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2310020H20Rik; ISCU2; Nifu; Nifun

Summary: Predicted to enable 2 iron, 2 sulfur cluster binding activity; ferrous iron binding activity; and molecular adaptor activity. Predicted to be involved in several processes, including negative regulation of iron ion import across plasma membrane; positive regulation of aconitate hydratase activity; and positive regulation of mitochondrial electron transport, NADH to ubiquinone. Located in mitochondrion. Orthologous to human ISCU (iron-sulfur cluster assembly enzyme). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in adrenal adult (RPKM 128.4), kidney adult (RPKM 126.9) and 28 other tissues

Orthologs: human

Gene size: 5871bp

Exon count: 5