Full name: Kruppel-like factor 15

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 1810013I09Rik; CKLF; KKLF; hlb444

Summary: Enables DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Involved in cardiac muscle hypertrophy in response to stress; glomerular visceral epithelial cell differentiation; and negative regulation of peptidyl-lysine acetylation. Acts upstream of or within several processes, including cellular glucose homeostasis; positive regulation of glucose import; and response to insulin. Located in nucleus. Is expressed in several structures, including central nervous system; cranium; early conceptus; metanephros; and nose. Used to study aortic aneurysm. Orthologous to human KLF15 (Kruppel like factor 15). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in liver adult (RPKM 36.3), kidney adult (RPKM 26.2) and 20 other tissues

Gene size: 31001bp

Exon count: 8