Full name: solute carrier family 8 member A3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: NCX3

Summary: This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013]

Expression: Biased expression in brain (RPKM 2.0), adrenal (RPKM 0.3) and 4 other tissues

Gene size: 145191bp

Exon count: 12