SLC8A2 solute carrier family 8 member A2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 6543)
Source: NCBI Gene (ID 6543)
Symbol: SLC8A2
Full name: solute carrier family 8 member A2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: NCX2
Summary: Predicted to enable calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium:sodium antiporter activity. Predicted to be involved in several processes, including inorganic cation transmembrane transport; learning or memory; and regulation of short-term neuronal synaptic plasticity. Predicted to act upstream of or within several processes, including modulation of chemical synaptic transmission; regulation of action potential firing pattern; and response to ischemia. Part of presynapse. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in brain (RPKM 19.6), endometrium (RPKM 1.5) and 1 other tissue
Orthologs: mouse
Gene size: 43877bp
Exon count: 10