Full name: membrane associated ring-CH-type finger 7

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: AXO; AXOT; MARCH-VII; MARCH7; RNF177

Summary: MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010]

Expression: Ubiquitous expression in esophagus (RPKM 29.0), testis (RPKM 28.8) and 25 other tissues

Gene size: 58522bp

Exon count: 17