Suv39h2 suppressor of variegation 3-9 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 64707)
Source: NCBI Gene (ID 64707)
Symbol: Suv39h2
Full name: suppressor of variegation 3-9 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 4930507K23Rik; D030054H19Rik; D2Ertd544e; KMT1B
Summary: Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and histone-lysine N-methyltransferase activity. Involved in histone H3-K9 methylation; negative regulation of circadian rhythm; and negative regulation of transcription, DNA-templated. Acts upstream of or within histone H3-K9 methylation and male meiotic nuclear division. Located in heterochromatin and nucleus. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and limb. Orthologous to human SUV39H2 (SUV39H2 histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E11.5 (RPKM 5.6), placenta adult (RPKM 3.1) and 21 other tissues
Orthologs: human
Gene size: 19234bp
Exon count: 6