Full name: sex hormone binding globulin

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ABP; SBP; TEBG

Summary: This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Expression: Biased expression in liver (RPKM 11.7), testis (RPKM 2.8) and 3 other tissues

Gene size: 19309bp

Exon count: 10