Full name: claspin

Gene type: protein coding

RefSeq status: REVIEWED

Summary: The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Expression: Broad expression in bone marrow (RPKM 2.6), testis (RPKM 2.4) and 16 other tissues

Gene size: 49766bp

Exon count: 26