Full name: cell death inducing DFFA like effector c

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CIDE-3; CIDE3; FPLD5; FSP27

Summary: This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Expression: Biased expression in fat (RPKM 484.8), small intestine (RPKM 36.2) and 1 other tissue

Gene size: 13544bp

Exon count: 9