Bco1 beta-carotene oxygenase 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 63857)
Source: NCBI Gene (ID 63857)
Symbol: Bco1
Full name: beta-carotene oxygenase 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Mus musculus
Also known as: Bcdo; Bcdo1; Bcmo1; CMO1; Cmoi; beta-CD; betaCMOOX
Summary: Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules. Two alternatively spliced variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
Expression: Biased expression in testis adult (RPKM 9.3), liver E18 (RPKM 2.0) and 6 other tissues
Orthologs: human
Gene size: 37870bp
Exon count: 12