Full name: retinoid X receptor gamma

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: NR2B3; RXR-gamma; RXRC; RXRgamma

Summary: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]

Expression: Broad expression in heart (RPKM 1.5), adrenal (RPKM 1.5) and 22 other tissues

Gene size: 44205bp

Exon count: 12