Full name: retinoid X receptor beta

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DAUDI6; H-2RIIBP; NR2B2; RCoR-1; RXR-beta; RXRbeta

Summary: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Expression: Ubiquitous expression in thyroid (RPKM 13.3), spleen (RPKM 12.9) and 25 other tissues

Gene size: 7266bp

Exon count: 11