Full name: ribosomal protein S6 kinase A1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: HU-1; MAPKAPK1; MAPKAPK1A; RSK; RSK1; p90Rsk

Summary: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Expression: Broad expression in small intestine (RPKM 31.6), duodenum (RPKM 29.3) and 21 other tissues

Gene size: 45265bp

Exon count: 26