Full name: AGBL carboxypeptidase 5

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: CCP5; RP75

Summary: This gene encodes a metallocarboxypeptidase involved in protein deglutamylation and a member of the peptidase M14 family of proteins. The encoded protein has been described as a "dual-functional" deglutamylase that can remove glutamate residues from both carboxyl termini and side chains of protein substrates. This deglutamylase activity may be important in antiviral immunity. Mutations in this gene are associated with retinitis pigmentosa. [provided by RefSeq, Jul 2016]

Expression: Biased expression in testis (RPKM 145.3), thyroid (RPKM 14.3) and 7 other tissues

Gene size: 20255bp

Exon count: 20