Full name: BAF chromatin remodeling complex subunit BCL7A

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: BCL7; SMARCJ1

Summary: This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in brain (RPKM 10.8), lymph node (RPKM 10.6) and 25 other tissues

Gene size: 40161bp

Exon count: 6