PPCDC phosphopantothenoylcysteine decarboxylase [ Homo sapiens (human) ] - Gene - Data resources

60490

PPCDC phosphopantothenoylcysteine decarboxylase [ Homo sapiens (human) ]
Source: NCBI Gene (ID 60490)

Symbol: PPCDC

Full name: phosphopantothenoylcysteine decarboxylase

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: MDS018; PPC-DC; coaC

Summary: Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008]

Expression: Ubiquitous expression in bone marrow (RPKM 1.6), appendix (RPKM 1.5) and 25 other tissues

Orthologs: mouse

Gene size: 27137bp

Exon count: 7