RFC3 replication factor C subunit 3 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 5983)
Symbol: RFC3
Full name: replication factor C subunit 3
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: RFC38
Summary: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in lymph node (RPKM 1.9), bone marrow (RPKM 1.4) and 24 other tissues
Orthologs: mouse
Gene size: 159229bp
Exon count: 15