BCL2 BCL2 apoptosis regulator [ Homo sapiens (human) ] - Gene - Data resources

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BCL2 BCL2 apoptosis regulator [ Homo sapiens (human) ]
Source: NCBI Gene (ID 596)

Symbol: BCL2

Full name: BCL2 apoptosis regulator

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: Bcl-2; PPP1R50

Summary: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Expression: Broad expression in thyroid (RPKM 21.9), spleen (RPKM 9.1) and 20 other tissues

Orthologs: mouse

Gene size: 196745bp

Exon count: 4