Full name: coagulation factor XII (Hageman factor)

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: FXII; HAF

Summary: This gene encodes a glycoprotein coagulation factor that plays an important role in the intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that is autoactivated upon contact with negatively charged surfaces or misfolded protein aggregates. Mice lacking the encoded protein have a severe defect in forming stable fibrin clots. [provided by RefSeq, Apr 2015]

Expression: Biased expression in liver adult (RPKM 284.9), liver E18 (RPKM 133.3) and 2 other tissues

Gene size: 8847bp

Exon count: 14