Full name: protein tyrosine phosphatase non-receptor type 4

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: MEG; PTPMEG; PTPMEG1

Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in thyroid (RPKM 7.2), brain (RPKM 5.8) and 24 other tissues

Gene size: 224978bp

Exon count: 27