ZFAT zinc finger and AT-hook domain containing [ Homo sapiens (human) ]
Source: NCBI Gene (ID 57623)
Source: NCBI Gene (ID 57623)
Symbol: ZFAT
Full name: zinc finger and AT-hook domain containing
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: AITD3; ZFAT1; ZNF406
Summary: This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
Expression: Broad expression in placenta (RPKM 4.4), kidney (RPKM 1.1) and 17 other tissues
Orthologs: mouse
Gene size: 354552bp
Exon count: 26