Full name: microtubule associated scaffold protein 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ATBP; ATIP; ATIP3; ICIS; MP44; MTSG1

Summary: This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]

Expression: Ubiquitous expression in heart (RPKM 12.1), ovary (RPKM 11.4) and 24 other tissues

Gene size: 157720bp

Exon count: 22