Full name: prostaglandin F receptor

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: FP

Summary: The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Expression: Broad expression in endometrium (RPKM 7.8), urinary bladder (RPKM 5.1) and 16 other tissues

Gene size: 49728bp

Exon count: 5